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The Windows registry has always been known as a difficult thing to deal with.  Even experienced computer techs tend to shy away from doing work on the registry because of the potential for severe consequences.  The registry is made up of files and folders that programs and Windows make in order to run consistently.  The registry controls things like individual user settings and permissions, as well as more mundane things like wallpaper and mouse click speed.

If you need to clean the registry then I advise you to read some registry cleaner reviews for more information on which programs are considered the best.  You don’t want to use inferior software when dealing with the Windows registry.